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Back To Normal: Surgery Improves Outcomes For Spine Patients
People with the spine disease called degenerative spondylolisthesis -- who choose surgical treatment -- experience substantially greater relief from pain over time compared to those who do not have surgery, according to a study published in the June 2009 issue of The Journal of Bone and Joint Surgery (JBJS). In the past, physicians had been uncertain whether surgery provided significantly greater relief for patients, but these results help to confirm the advantages to surgery.
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Oncolytics Biotech(R) Inc. Announces Publication Of Research On Synergistic Activity Of Reovirus And Chemotherapy In NSCLC
Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) ("Oncolytics") reported today that Dr. Shizuko Sei et al. published the results of their work examining reovirus and chemotherapy against human non-small cell lung cancer (NSCLC). The paper, entitled "Synergistic Antitumor Activity of Oncolytic Reovirus and Chemotherapeutic Agents in Non-Small Cell Lung Cancer Cells" appears online in the July 14, 2009 issue of Molecular Cancer.
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What Is Huntington's Disease? What Causes Huntington's Disease?
Huntington"s disease is an incurable, hereditary brain disorder. It is a devastating brain disorder for which there is no currently "effective" treatment. Nerve cells become damaged, causing various parts of the brain to deteriorate. The disease affects movement, behavior and cognition - the affected individuals" abilities to walk, think, reason and talk are gradually eroded to such a point that they eventually become entirely reliant on other people for their care. Huntington"s disease has a major emotional, mental, social and economic impact on the lives of patients, as well as their families.
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AP/Washington Post Examines Experimental Malaria Vaccine, Mutant Mosquitoes To Combat Malaria

The AP/Washington Post examines attempts to create a live vaccine and mutant mosquitoes to fight malaria. During the 1990s, Sanaria CEO Stephen Hoffman "irradiated malaria-carrying mosquitoes to weaken the parasites inside them, and he and 13 colleagues subjected themselves to more than 1,000 bites," according to the AP/Washington Post. "Usually malaria parasites race to the liver and multiply before invading the bloodstream" and making their host sick, but these "weakened parasites" sat "harmlessly in the liver, unable to multiply but triggering the immune system to fend off later infections," the AP/Washington Post reports, adding that only one of the people in Hoffman"s test did not achieve immunity "when bitten by regular malaria-infected mosquitoes over the next 10 months." Hoffman said critics charged that turning his experiment into a vaccine was almost impossible and that he was "dismissed by 99 percent of the people in the malaria field." But, two weeks ago about 100 volunteers started receiving doses of Sanaria"s vaccine in a first-stage FDA-approved study. Aside from a vaccine, about "a dozen labs worldwide" are trying to combat malaria by breeding malaria-resistant mosquitoes, the AP/Washington Post reports. David O"Brochta"s lab at the University of Maryland is working on ways to enable mosquitos to pass on malaria parasite resistance to their offspring, according to the AP/Washington Post. To be effective, "a malaria-resistance gene would have to spread a lot faster through mosquito populations," as a result the O"Brochta lab"s main focus is how to speed that up. Sanaria is working on a mosquito that can harbor double the number of immature parasites, to facilitate harvesting the parasites for the vaccine. O"Brochta is working on something similar and is trying to switch off a gene that protects the mosquito when it eats malaria-infected human blood. However, O"Brochta said, "No one has ever made transgenic mosquitoes with this gene knocked out," adding, "We want to cripple its immune system so when it takes an infected meal, it gets infected at very high levels" (Neergaard, AP/Washington Post, 6/8). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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