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The U.S. Food and Drug Administration provided further updated safety information on a class of asthma drugs known as leukotriene modifiers. The FDA has requested that manufacturers include a precaution in the drug prescribing information (drug labeling) regarding neuropsychiatric events (behavior, mood changes) that have been reported in some persons taking montelukast (Singulair), zafirlukast (Accolate), and zileuton (Zyflo and Zyflo CR).
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Magee-Womens Hospital Awarded For Achievements In Reducing Elective Induced Labor
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PeriCor Therapeutics Reports Positive Preclinical Results Of GP531 At The European Heart Failure Congress In Nice
PeriCor Therapeutics, Inc. announced that positive preclinical results of its novel cardioprotective agent, GP531, were reported in a poster presentation by Hani N. Sabbah, Ph.D., at the European Heart Failure Congress 2009 in Nice, France. The study was funded by PeriCor Therapeutics, Inc. and conducted by Dr. Sabbah and colleagues at the Division of Cardiovascular Medicine of the Henry Ford Health System, Detroit, Michigan. GP531 is an investigational drug under development by PeriCor Therapeutics under an Investigational New Drug (IND) application.
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Advanced Technologies Pump Growth Into European Cardiac Rhythm Management Market, Affirms Frost & Sullivan, UK

The incidence of cardiovascular disease is rising due to factors such as ageing, obesity, smoking and other cardiac ailments. Each year cardiovascular diseases cause over 4.3 million deaths, accounting for 48 per cent of all mortalities in Europe. As a result, the European cardiac rhythm management (CRM) market offers significant growth potential. The approval of implantable CRM therapy for congestive heart failure by means of cardiac resynchronisation therapy devices; regulatory approval of advanced technologies such as ablation catheters and cost benefits accrued to the national healthcare system are invigorating the expansion of the CRM market. New analysis from Frost & Sullivan (http://www.medicaldevices.frost.com), Western European Cardiac Rhythm Management Market, finds that the market earned revenues of $3.4 billion in 2008 and is estimated to reach $7.3 billion in 2015. The following segments are covered in this research: pacemakers, implantable cardioverter defibrillators, cardiac resynchronisation devices and ablation catheters and pacing leads. "Collaborative partnerships, technological innovation and device scalability will determine the future of the European CRM market," notes Frost & Sullivan Research Associate Sreevidhya Praveen. "To position a company for future growth, building an effective channel to profitably distribute lower cost equipment to new, emerging users is absolutely essential. At the same time, international manufacturers should aim to establish alliances with smaller participants for the sale and distribution of their products." The major segments of the CRM market are achieving rapid penetration, indicative of a flourishing space for CRM devices. Certain segments such as CRT-P and leads, while expanding gradually, are still exhibiting a positive growth rate. The CRM industry reveals natural, organic growth with all market participants set to make revenue gains. The CRM market consists of a select few market participants, trying to sell high-cost, life-saving devices. Each manufacturer utilises bipolar leads, bi-ventricular pacing devices, high rate adaptive pacing, and sophisticated programmers to capture and translate data. The price difference between these devices is fairly marginal. The inability of niche participants to distinguish themselves is a characteristic of the market. Without product differentiation, they have been unable to capture the attention of consumers. "Each manufacturer strives to introduce their own device features and innovations to differentiate their devices; it essentially amounts to how these devices are perceived in the mind of specialists," explains Praveen. "It is critical for companies to brand their technology and establish themselves in the minds of consumers." Device mortality remains a concern for end users. Battery life is one of the key factors that contribute to device longevity. Trends related to thin-film battery technology and high-energy batteries are positive, auguring well for market prospects. However, there needs to be greater focus on developing the durability of batteries and the factors that contribute to device longevity. Moreover, manufacturers should continually monitor the market and steadily invest in R&D to promote product innovation and differentiation. Western European Cardiac Rhythm Management Market is part of the Medical Devices Growth Partnership Service programme, which also includes research in the following markets: European Bone Growth and Spinal Fusion Stimulators Market, European Tissue Sealants and Topical Hemostats Market and European Market for Biopsy Devices. All research services included in subscriptions provide detailed market opportunities and industry trends that have been evaluated following extensive interviews with market participants. Interviews with the press are available. Frost & Sullivan


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