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Managing Incontinence After A Stroke - May Is Stroke Awareness Month
Approximately 800,000 people suffer a stroke in the United States each year, nearly three-quarters of which occur in people over 65 years old. On average, someone in the U.S. suffers a stroke every 40 seconds.
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Carbapenems And Other Agents That Provide Broad-Spectrum Activity Are Preferred By Surveyed Physicians For The Treatment Of Intra-Abdominal Infections
Arlington Medical Res (AMR) and Decision Res find that surveyed physicians will increase prescribing of Wyeth"s Tygacil, Merck"s Invanz and Johnson & Johnson"s Doribax in the next five years for the treatment of intra-abdominal infections because of their potent broad-spectrum activity and efficacy against gram-negative and anaerobic organisms.
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Bacteria Are First Sensed By Cells Lining Blood Vessels, Not Immune Cells
Paul Kubes and colleagues, at the University of Calgary, Canada, have provided evidence in mice to refute the paradigm that the initial phase of the immune response to infection with Gram-negative bacteria (the recruitment of immune cells known as neutrophils to the site of infection) is triggered following immune sentinel-cell recognition of the bacterial molecule LPS via the protein TLR4. Rather, the researchers found that LPS recognition by TLR4 on the cells that line blood vessels (endothelial cells) is the crucial event that initiates neutrophil recruitment and bacterial clearance in mice.
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Goal Of Good Quality Medicines Advanced By New USP Agreement With 9 ASEAN Countries

Furthering its mission to improve the quality of medicines worldwide, the U.S. Pharmacopeial (USP) Convention has signed a cooperative agreement with nine countries belonging to the Association of Southeast Asian Nations (ASEAN). In a drive to strengthen capacities and certification status of national drug quality control laboratories, officials from Cambodia, Laos, Myanmar, Singapore, Vietnam, Indonesia, Malaysia, the Philippines and Thailand had formed an ASEAN Reference Materials Working Group (ARMWG) to focus on modern, international measurement standards for medicines in the region. The agreement with USP is the culmination of discussions that started in 2008 with the aim of improving the production, precision and quality of ASEAN Reference Substances (ARS). According to Roger L. Williams, M.D., chief executive officer of USP, "This agreement is a milestone in our shared goal of improving the quality of medicines in the region and around the world. We all recognize the importance of long-term strategies to ensure the availability of good quality medicines, and we believe that by working together that goal becomes more readily achievable." At an event to commemorate the signing of the agreement, Mr. Niphon Popattanachai, the deputy director-general of the department of medical sciences at the Thai Ministry of Public Health, said, "We have been working for many years to strengthen the pharmaceutical sector within ASEAN countries, and to become more self-reliant in training scientific staff within our drug quality control laboratories. Our partnership with USP-as well as with the World Health Organization (WHO), the British National Institute for Biological Standards and Control, the Japan Pharmaceutical Manufacturers Association, and others-will offer valuable collaborative res and scientific exchange." Areas of potential collaboration under the agreement include working toward WHO and ISO measurement standards for medicines; promoting ISO certification for ASEAN drug quality control laboratories; support for joint studies and scientist exchange programs; and mutual development of ways to combat counterfeit and substandard medicines. Francine Pierson US Pharmacopeia


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