Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Buy dildos and sex toys.
Popular Articles

How Genetics Influences Humans When Choosing A Mate
New light has been thrown on how humans choose their partners, a scientist told the annual conference of the European Society of Human Genetics on May 25. Professor Maria da GraÃýa Bicalho, head of the Immunogenetics and Histocompatibility Laboratory at the University of Parana, Brazil, says that her research had shown that people with diverse major histocompatibility complexes (MHCs) were more likely to choose each other as mates than those whose MHCs were similar, and that this was likely to be an evolutionary strategy to ensure healthy reproduction.
buy viagra
A Selection Of Editorials And Opinions
The Slow, Slow Pulse Of The Deliberative Body The Washington Post
News of the day
What Is Ovarian Cancer? What Causes Ovarian Cancer?
Ovarian cancer is any cancerous growth that may occur in different parts of the ovary. The majority of ovarian cancers arise from the epithelium (outer lining) of the ovary. According to the American Cancer Society it is the 8th most common cancer among women in the USA (excluding non-melanoma skin cancers). In the UK ovarian cancer is the fifth most common cancer among females, after breast cancer, bowel cancer, lung cancer and uterine cancer (cancer of the uterus).
Oncology

Increased Vascular Endothelial Growth Factor Expression In Patients With Bladder Pain Syndrome/Interstitial Cystitis

UroToday.com - Angiogenesis is thought to be important in many chronic inflammatory disorders, including diabetic retinopathy, atherosclerosis, and inflammatory bowel disease. It has also been suggested that the angiogenic components of these diseases contribute to and exacerbate disease conditions. Increased levels of vascular endothelial growth factor (VEGF) have been detected in patients with asthma and have been shown to be correlated with the severity of the disease. Anti-VEGF therapy has been shown to ameliorate inflammation in animal models of chronic inflammatory bowel disease. This background forms the prelude to a very interested study by Kiuchi and colleagues from Osaka, Japan. The authors note that VEGF is a crucial angiogenic factor, and its secretion is strictly regulated to form functional vessel networks. Pericytes are perivascular cells that wrap around microvessels and contact endothelial cells through discontinuities in the shared basement membrane. When vessels lose pericytes, they become tortuous and hemorrhagic. Abnormal activity of VEGF contributes to insufficient coverage of pericytes, resulting in leaky and hemorrhagic vessels. Kiuchi and coworkers examined biopsy specimens from 30 patients with BPS/IC who demonstrated glomerulations on hydrodistention, and compared them with biopsies from 10 control patients who had isolated bladder tumors and no symptoms of voiding dysfunction. None of the control patients had glomerulations after distention. Immunohistochemical analysis for VEGF expression, microvessel density and immature microvessels was performed. Pericyte coverage of microvessels in the specimens was used as an indicator of mature microvessels, and pericytes were identified by double-immunohistochemistry for CD34 and í±-smooth muscle actin. The researchers generated data that allowed them to conclude that there is an increased VEGF and immature vascularization in the bladder biopsies from patients with BPS/IC, and VEGF expression was associated with the degree of pain experienced by the patients. Taken together, Kiuchi believes that VEGF might contribute to pain and promote the formation of immature vessels in the bladder of patients with BPS/IC. This increased immature vascularization might have a potential role in glomerulations in these patients. Kiuchi H, Tsujimura A, Takao T, Yamamoto K, Nakayama J, Miyagawa Y, Nonomura N, Takeyama M, Okuyama A BJU Int. 2009 Mar 4. (Epub ahead of print) doi:10.1111/j.1464-410X.2009.08467.x Written by UroToday.com Contributing Editor Philip M. Hanno, MD, MPH UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice. To access the latest urology news releases from UroToday, go to: www.urotoday.com Copyright © 2009 - UroToday


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009