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'Hijacking Mechanism' Of HIV-1' Pinpointed By McGill/JGH Researchers
Researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal"s Jewish General Hospital - along with colleagues at the University of Manitoba and the University of British Columbia - may have found a chink in the armour of the human immunodeficiency virus type 1 (HIV-1), the microorganism which causes AIDS. They have pinpointed the key cellular machinery co-opted by HIV-1 to hijack the human cell for its own benefit. Their study was published in May in the Journal of Biological Chemistry.
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Obesity Threshold Is Lowered For People In India
The threshold for being overweight or obese has been lowered in India, as people of South Asian origin are more likely than white people to develop obesity-related conditions such as Type 2 diabetes and heart disease.
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Growing Immature Human Egg Cells To Nearly Mature Egg In Laboratory Could Save Cancer Patients' Fertility
The tiny translucent egg nestled in the special laboratory gel was a mere 30 days old, but its four-week birthday caused researchers to quietly celebrate. This was the first time anyone had successfully grown a woman"s immature egg cells, contained in a tiny sac called a follicle, to a healthy and nearly mature egg in the laboratory. When an egg is fully mature, it is ready to be fertilized.
Cardiovascular

Older Cancer Patients Have More Frailty Than Other Seniors

Older people with a history of cancer are more likely to have disabilities and be frail and vulnerable than older adults who have not had cancer, according to a study in the Journal of the National Cancer Institute, published online July 29. The prevalence of frailty and vulnerability among older cancer patients will pose an increasing challenge for physicians as the population ages. By the year 2030, persons who are older than 65 years are projected to make up 70% of cancer patients and have 65% of cancer deaths. Supriya Gupta Mohile, M.D., from the James P. Wilmot Cancer Center at the University of Rochester in N.Y., and colleagues used data in the 2003 Medicare Current Beneficiary Survey to evaluate whether non-skin cancer was independently associated with vulnerability and frailty. They found that survey respondents with a history of non-skin cancer had statistically significantly more limitations in the activities of daily living and other measures of frailty and vulnerability than those who had not had cancer. The authors conclude that their study "establishes the increased baseline prevalence of factors among cancer patients that have been associated with adverse health outcomesò€¦" They also note that the study is "a first step in highlighting the importance of "staging the aging" (i.e., assessing factors that characterize physiological and functional capacity) among cancer patients by the use of geriatric assessment." Steve Graff Journal of the National Cancer Institute


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