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Amyloid Aggregations And Tau Pathology Reflected By Cortical Thickness In The Default Network Of MCI And AD
Alzheimer"s disease patients show a relentless decline in memory over the course of the disease, which is accompanied by both brain atrophy and by characteristic deposits in the brain tissue called amyloid plaques and neurofibrillary tangles. Researchers from the Chinese Academy of Sciences studied a large database, collected in the US, of patients with Alzheimer"s or memory complaints who had MRI scans and had spinal taps to collect cerebrospinal fluid, which is in the brain and spinal chord. By examining the CFS they could measure the amounts of the substances that make p plaques and tangles, and related this to brain atrophy. They found that the amount of plaque and tangle-producing chemicals in the cerebrospinal fluid correlated with brain tissue loss in selective regions of the brain which are typically affected in Alzheimer"s disease. The brains in these regions had thinned out suggesting that brain cells had died. These regions are important for memory and are typically active when the brain is at rest. Using these techniques may ultimately help identify early markers of disease in Alzheimer"s, potentially indicating who is likely to develop Alzheimer"s before memory loss is critical.
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UNT Health Science Center's Groundbreaking Research Applied To Protecting Brain After Traumatic Injury
In groundbreaking research, scientists at the University of North Texas Health Science Center at Fort Worth have determined that rapid estrogen administration can protect the brain following brain injury. These findings are now being tested on human trauma patients in North Texas.
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Second Face Transplant Man Speaks Out, US
James Maki, the second person in the US to receive a face transplant, has been telling his story in the hope that it will encourage more people to
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Premier Healthcare Alliance Recognizes Nation's Top Hospitals For Commitment To High-quality Patient Care, Operational Efficiency

The Premier healthcare alliance has recognized the nation"s top hospitals for their commitment to outstanding patient care and operational efficiency with the 2009 Premier Award for Quality (AFQ). Premier announced the 23 winners of the award, out of more than 3,796 eligible hospitals nationwide, at Premier"s annual Breakthroughs Conference and Exhibition in Anaheim, Calif. The AFQ recognizes leading healthcare organizations that efficiently provide outstanding patient care and consistently set the standard in clinical excellence nationwide. Distinguished by its consideration of performance-based criteria, including clinical quality outcomes, re utilization, and clinical process indicators, the AFQ measures top performers at the overall hospital level. "The Award for Quality honors the efforts of our nation"s leading hospitals to provide superior quality and operational efficiency," said Susan DeVore, Premier incoming president and CEO. "We"re thrilled to celebrate the efforts of these facilities as they improve the health of the communities they serve." All acute care inpatient facilities in the United States that submitted data to the Centers for Medicare & Medicaid Services (CMS) and the CMS Hospital Compare project were considered for the AFQ. Using MedPar 2007 data, Quality and Efficiency Indexes were calculated for 62 disease groups and at the overall hospital level. Quality was measured by the incidence of three adverse outcomes: mortality, morbidity and complications, which are combined into a single Quality Index using the preference weightings from the Corporate Hospital Rating Project. The efficiency index was generated using length of stay to proxy for re utilization. Acute care facilities attaining the top 1 percent designation are identified as having scores in the top two quintiles for process of care and in 10 out of 62 disease groups and at the overall hospital level for quality and efficiency. Additionally, hospitals had measures for quality and efficiency that were equal to or exceeded expected outcomes. 2009 Award for Quality winners are: SSM DePaul Health Center - Bridgeton, Mo. St. Elizabeth Health Center - Youngstown, Ohio Hoag Memorial Hospital - Newport Beach, Calif. Memorial Regional Hospital - Hollywood, Fla. Winchester Hospital - Winchester, Mass. Hackensack University Medical Center - Hackensack, N.J. Good Samaritan Hospital - Cincinnati Saint Vincent Health Center - Erie, Pa. Albert Einstein Medical Center - Philadelphia Allegiance Health - Jackson, Mich. Mercy General Hospital - Sacramento, Calif. Beth Israel Deaconess Medical Center - Boston Sound Shore Medical Center of Westchester - New Rochelle, N.Y. Joint Township District Memorial Hospital - Saint Marys, Ohio St. Vincent Charity Hospital - Cleveland Lakewood Hospital - Lakewood, Ohio The Western Pennsylvania Hospital - Pittsburgh Memorial Hospital - Colorado Springs, Colo. Penrose/St. Francis Healthcare - Colorado Springs, Colo. Rush University Medical Center - Chicago Paoli Memorial Hospital - Paoli, Pa. Medical University of South Carolina - Charleston, S.C. Maury Regional Hospital - Columbia, Tenn. Premier Inc.


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