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International Stem Cell Collaboration Results In Discovery Of Promising New Stem Cell Type
DaVinci Biosciences LLC in collaboration with University of Utah, Southern California Center for Regenerative Medicine and Omni Hospital in Ecuador, announce the discovery of a previously unidentified stem cell population from adult human testis in Biochemical and Biophysical Research Communications (BBRC), an international peer-reviewed journal focused on the rapid dissemination of timely and significant experimental results in diverse fields of biological research. Termed gonadal stem cells (GSCs) these adult derived stem cells, unlike previous reported population of stem cells found within the testis, have been found to demonstrate adult stem cell properties. Published in the current journal of Biochemical and Biophysical Research Communications, the data from this collaborative study describes a multipotent adult stem cell population that has the capacity to readily differentiate into multiple cell types. The study evolved from an international collaboration aimed at identifying novel cell populations at different geographical laboratory locations and for different HLA types.
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Modifiable Hip Fracture Complications Contribute To Mortality, Institute For Aging Research Finds
Potentially modifiable post-fracture complications, including pneumonia and pressure ulcers, are associated with an increased risk of death among nursing home residents who have suffered a hip fracture, according to a new study conducted by scientists at the Institute for Aging Research at Hebrew SeniorLife.
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Prevention Program Helps Teens Override A Gene Linked To Risky Behavior
A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), components of the National Institutes of Health, supported the study, which appears in the May/June issue of Child Development.
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Study Sees Transient Heart Dysfunction In Some Long-Distance Runners

A new study using advanced cardiac imaging technology indicates that cardiac abnormalities experienced by some marathon runners following competition are temporary, and do not result in damage to the heart muscle. The study, conducted by researchers at the University of Manitoba, marked the first use of cardiac magnetic resonance imaging, or CMR, in a post-marathon setting. The research was presented on Sunday, May 17, at the 105th International Conference of the American Thoracic Society in San Diego. "Although previous studies of marathon runners have demonstrated biochemical evidence of cardiac injury and have correlated these findings with echocardiographic evidence of cardiac dysfunction, this was the first time CMR has been used to further evaluate and understand the effects of marathon running on the heart," said study investigator Davinder S. Jassal, M.D., assistant professor of cardiology, radiology and physiology at St. Boniface General Hospital Research Centre in Winnipeg. The study examined the cardiac health of 14 runners who participated in the full 2008 Manitoba Marathon in Winnipeg, Canada. All runners were classified, for purposes of the study, as "non-elite," meaning they participated on a casual, non-professional basis, with limited or no training. Prior to the marathon, each study participant underwent a comprehensive health screening, including blood tests to determine the levels of cardiac biomarkers, factors present in the blood that reflect the health of the heart muscle. Following the race, additional blood samples were taken and echocardiograms and CMR were performed. Earlier studies have confirmed that cardiac biomarkers are elevated in many casual, non-professional athletes following competition, indicating possible damage to the heart muscle. In this study, echocardiograms and CMR performed immediately after competition revealed abnormalities, including irregularities in diastolic filling (relaxation abnormalities) on both sides of the heart and a decrease from 64 percent to 43 percent in the pumping function of the right ventricle. Although the cardiac biomarkers were elevated post marathon, there was no evidence of direct permanent injury to the heart muscle on CMR imaging. "By using CMR, we were able to definitively show that these fluctuations do not result in any true damage of the heart, and the right ventricular dysfunction is transient, recovering one week following the race," Dr. Jassal noted. The researchers are planning additional studies to determine whether these abnormalities may result in permanent damage in runners who participate in more than one marathon during a 12-month period. Keely Savoie American Thoracic Society


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