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Children Denied Immunizations At Increased Risk Of Whooping Cough
Children of parents who refuse vaccines are 23 times more likely to get whooping cough compared to fully immunized children, according to a new study led by a vaccine research team at Kaiser Permanente Colorado"s Institute for Health Research.
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Supreme Court Nominee Sotomayor Prepares For Meetings With Key Senators
Supreme Court nominee Judge Sonia Sotomayor is scheduled to meet with key senators today as Republican leaders indicate that they will try to slow her confirmation process over the summer, the Washington Post reports. Sotomayor, in preparation for her meetings, has been working with White House lawyers to complete a 10-page Senate questionnaire, which aims to reveal details of her legal work, professional associations, personal finances, speeches, and legal and other writings. White House officials said the document will be finished "in the next couple of days." Senate Majority Leader Harry Reid (D-Nev.) said that he will provide Sotomayor"s background information to Republicans "as quickly as possible," adding that he "want[s] to make sure she"s ready to go" when the next Supreme Court term begins in October. Sotomayor is scheduled to meet today with Reid, Senate Minority Leader Mitch McConnell (R-Ky.), Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) and the panel"s ranking member, Jeff Sessions (R-Ala.). She also is scheduled to meet with Sens. Jon Kyl (R-Ariz.), Richard Durbin (D-Ill.), and New York Democrats Charles Schumer and Kirsten Gillibrand, the Post reports.While Sotomayor prepares for her meetings, Republican leaders indicated that they will try to impede President Obama"s push to confirm her before the Senate leaves for summer recess on Aug. 7. McConnell said that the GOP will determine its own schedule regarding Sotomayor"s confirmation, adding that although the GOP will "insist that the confirmation process be conducted in a fair and professional manner, ... respectful doesn"t mean rushed." Senior Senate aides from both parties said that a deal to expedite the confirmation process is unlikely, despite informal negotiations between Sessions and Leahy (Fletcher/Murray, Washington Post, 6/2). Sessions said it would be his "preference" for a confirmation after the August recess but before October. He added that there are "some things that have been raised that we need to explore" and that Sotomayor "deserves an opportunity to deal with the complaints against her" (Rushing, The Hill, 6/1).Conservative Groups Push for Filibuster According to the New York Times "The Caucus," a coalition of conservative groups recently sent a letter to McConnell urging Republicans to filibuster Sotomayor"s confirmation. The letter, which was obtained by the Times, is signed by a range of conservative groups, including antiabortion-rights groups, gun-rights advocates, evangelical leaders and others. Manuel Miranda, a former judicial adviser to former Senate Majority Leader Bill Frist (R-Tenn.), organized the letter. Although Miranda has criticized Democratic filibusters in the past, he said that a Republican filibuster of Sotomayor would help the GOP promote its differences with the Democratic Party on judicial philosophy and the role of the courts. However, Senate Republican leaders thus far have shown little interest in a filibuster, according to the "The Caucus" (Savage, "The Caucus," New York Times, 6/1). The Post reports that the GOP likely does not have enough votes to block Sotomayor"s confirmation with a filibuster, but Republicans could be able to slow the process until September. In this case, Sotomayor still would be able to take her place on the bench when the court reconvenes Oct. 1 (Washington Post, 6/2).The AP/USA Today reports that Republicans are taking a "two-sided strategy" in which they are urging for a respectful debate against Sotomayor while still allowing conservative commentators -- such as Rush Limbaugh and former House Speaker Newt Gingrich (R-Ga.) -- to criticize her, the AP/USA Today reports. By allowing the political attacks from commentators, Republicans who are facing re-election "can avoid potential backlash if they derail a historic nomination," the AP/USA Today reports (AP/USA Today, 6/1).
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Merck KGaA Submits Application For Cladribine Tablets As Multiple Sclerosis Therapy In Europe
Merck KGaA announced the submission of a marketing authorization application (MAA) to the European Medicines Agency (EMEA) for Cladribine Tablets, Merck"s proprietary investigational oral formulation of cladribine, as a therapy for patients with relapsing-remitting multiple sclerosis (MS). Cladribine Tablets could become the first orally administered disease-modifying therapy available for patients with MS, as all disease-modifying therapies currently approved for the treatment of MS are injectable.
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Warning Issued Over Proposed Drug Company Promotion Of Medicines To Public, UK

Drug companies may exploit new rules to promote their products to the public but present it as mere provision of information, according to an editorial published this week in the Drug and Therapeutics Bulletin (DTB). Direct advertising of prescription-only medicines to the public is currently not allowed in the European Union (EU), but this position may be undermined by proposals from the European Commission (EC). The proposals, if agreed, would allow drug companies new opportunities to present the public with information about prescription-only medicine through the internet or yet-to-be-defined "health-related publications." The DTB editorial is concerned about the proposals, which it suggests would permit direct advertising to the public in spite of the EU-wide ban. It is proposed that each EU member state would ensure the companies providing the information were monitored and this could involve self-regulation by the companies. "A key concern about these ideas is the intrinsic difficulty in distinguishing between advertising of prescription-only medicines to the public (which would still be banned) and proactive provision of non-promotional information about such products," says the editorial. The UK medicines regulator, the Medicines and Healthcare products Regulatory Agency, is currently carrying out a public consultation on this issue - due to finish on August 14 - but supports the principle of allowing the pharmaceutical industry to give patients more information about medicines. DTB, however, cites the negative experience in the US with direct to consumer advertising, where "infringements of rules on information provision have tended to be detected far too late and where there have been difficulties in imposing effective penalties." The editorial concludes: "We believe that acceptance of the EC"s proposals would permit public dissemination of promotional information about prescription-only medicines, masquerading as "information provision"." Given the obvious conflict of interests, DTB concludes, it would be naç¯ve to think that the pharmaceutical industry would provide independent and reliable information to allow people to make informed choices about treatment. "How to misinform patients." DTB 2009; doi 10.1136/dtb.2009.07.0027 Drug And Therapeutics Bulletin


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